FolM, A New Chromosomally Encoded Dihydrofolate Reductase in Escherichia coli
AUTOR(ES)
Giladi, Moshe
FONTE
American Society for Microbiology
RESUMO
Escherichia coli (thyA ΔfolA) mutants are viable and can grow in minimal medium when supplemented with thymidine alone. Here we present evidence from in vivo and in vitro studies that the ydgB gene determines an alternative dihydrofolate reductase that is related to the trypanosomatid pteridine reductases. We propose to rename this gene folM.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=262705Documentos Relacionados
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