Foscarnet for suppression of human immunodeficiency virus replication.
AUTOR(ES)
Fletcher, C V
RESUMO
The effect of foscarnet against human immunodeficiency virus (HIV) was evaluated in nine HIV-infected individuals; six completed 28 days of induction therapy. The overall mean increase in CD4+ lymphocytes was 64 cells per mm3. The mean decline in the HIV antigen concentration was 108 pg/ml (P = 0.03), and suppression was related to systemic foscarnet exposure by a maximum-effect pharmacodynamic model.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=284505Documentos Relacionados
- The art gene product of human immunodeficiency virus is required for replication.
- Inhibitory effects of polyethers on human immunodeficiency virus replication.
- Entamoeba histolytica antigen-specific induction of human immunodeficiency virus replication.
- Oltipraz, an inhibitor of human immunodeficiency virus type 1 replication.
- The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication.