Frequent involvement of the fim-3 region in Friend murine leukemia virus-induced mouse myeloblastic leukemias.

AUTOR(ES)
RESUMO

fim-3 is a new proviral integration region involved in 23% (16 of 68) of Friend murine leukemia virus-induced myeloblastic leukemias. This region is distinct from 20 oncogenes and from putative oncogenes tested so far. Proviruses are integrated in a 16-kilobase region, always in the same orientation. No RNA expression of fim-3 was detected.

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