FtsZ ring formation in fts mutants.

AUTOR(ES)

Addinall, S G

RESUMO

The formation of FtsZ rings (Z rings) in various fts mutants was examined by immunoelectron microscopy and immunofluorescence. In two temperature-sensitive ftsZ mutants which form filaments with smooth morphology, the Z ring was unable to form. In ftsA, ftsI, and ftsQ mutants, which form filaments with an indented morphology, Z rings formed but their contraction was blocked. These results indicate that fully functional ftsA, ftsQ, and ftsI genes are not required for Z-ring formation and are unlikely to have a role in localization of the Z ring. The results also suggest that one function of the Z ring is to localize the activity of other fts gene products.

Documentos Relacionados

• Interactions between heterologous FtsA and FtsZ proteins at the FtsZ ring.
• Growth Rate-Dependent Regulation of Medial FtsZ Ring Formation
• In Vivo Characterization of Escherichia coli ftsZ Mutants: Effects on Z-Ring Structure and Function
• Aberrant Cell Division and Random FtsZ Ring Positioning in Escherichia coli cpxA* Mutants
• Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis