G (Gross) and H-2 Cell-Surface Antigens: Location on Gross Leukemia Cells by Electron Microscopy with Visually Labeled Antibody*

AUTOR(ES)
RESUMO

The hybrid-antibody method of locating cell-surface antigens in electron micrographs, with either ferritin or southern bean mosaic virus as the visual marker, was applied to the cells of a transplanted murine leukemia induced by Gross virus. The two antigens studied were (a) G (Gross) cell-surface antigen, which is a specific component of cells infected with Gross virus and is identified by cytotoxic hyperimmune C57BL/6 antiserum, and (b) H-2 antigen, which is the major histocompatibility determinant of the mouse.

Documentos Relacionados