Generation and Characterization of a Defined Mutant of Streptococcus suis Lacking Suilysin
AUTOR(ES)
Allen, Andrew G.
FONTE
American Society for Microbiology
RESUMO
A defined allelic-replacement mutant of the sly gene, encoding a thiol-activated cytolysin, from a European isolate of Streptococcus suis serotype 2 was generated and characterized. Unlike the parental strain, it is nonhemolytic, noncytotoxic for cultured macrophage-like cells, avirulent in a mouse infection model, yet only slightly attenuated in a porcine model of systemic infection.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=98215Documentos Relacionados
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