Genetic Interaction between Distinct Dobrava Hantavirus Subtypes in Apodemus agrarius and A. flavicollis in Nature

AUTOR(ES)

Klempa, Boris

FONTE

American Society for Microbiology

RESUMO

Dobrava virus (DOBV) occurs in two different rodent species, Apodemus flavicollis (DOBV-Af) and A. agrarius (DOBV-Aa). We sequenced the S and M genomic segments from sympatric DOBV-Af and DOBV-Aa strains which fell into two distinct genetic lineages. Molecular phylogenetic analyses gave evidence for genetic reassortment between S and M segments of DOBV-Af and DOBV-Aa and indicated homologous recombination events in DOBV evolution. DOBV-Af and DOBV-Aa are distinct but also subject to genetic exchanges that affect their evolutionary trajectories.

Documentos Relacionados

• Isolation of Dobrava Virus from Apodemus flavicollis in Greece
• Genetic Interaction between Dobrava and Saaremaa Hantaviruses: Now or Millions of Years Ago?
• Truncated Hantavirus Nucleocapsid Proteins for Serotyping Hantaan, Seoul, and Dobrava Hantavirus Infections
• DNA Profiling of B Chromosomes from the Yellow-necked Mouse Apodemus flavicollis (Rodentia, Mammalia)
• Interaction between heat shock protein DnaK and recombinant staphylococcal protein A.