Genetic rescue of muscle defects associated with a mutant Drosophila melanogaster tropomyosin allele.

AUTOR(ES)

Fyrberg, E A

RESUMO

We describe a genetic transformation system which should prove useful for investigating tropomyosin assembly and function. Muscle abnormalities associated with a defective tropomyosin allele were corrected by integrating the wild-type gene into germ line chromosomes. The transformation protocol permits application of directed mutagenesis techniques in investigations of contractile regulatory mechanisms.

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