Genomic and Phylogenetic Analysis of Hepatitis C Virus Isolates from Argentine Patients: a Six-Year Retrospective Study
AUTOR(ES)
Quarleri, J. F.
FONTE
American Society for Microbiology
RESUMO
Typing of hepatitis C virus (HCV) isolates from Argentine patients was performed by using different methodologies in a population of 243 patients. HCV subtype was assigned based upon restriction fragment length polymorphism (RFLP). HCV RNA genomes obtained from serum samples were classified as belonging to clade 1 (53.5%), 2 (23.0%), or 3 (8.6%); 14.8% of samples showed HCV mixed infections, more frequently implying different subtypes within the same clade. In addition to RFLP typing, phylogenetic relatedness among sequences from both 5′ untranslated region (n = 50) and nonstructural 5B coding region (n = 15) was established.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=87637Documentos Relacionados
- Genomic and Phylogenetic Analysis of Hepatitis C Virus Isolates from Argentine Patients: a Six-Year Retrospective Study
- Brazilian hepatitis B vaccine: a six-year follow-up in adolescents
- Six-Year Retrospective Follow-Up Study of Safe Screening Intervals for Sight-Threatening Retinopathy in Patients with Diabetes Mellitus
- Six-Year Molecular Analysis of Burkholderia cepacia Complex Isolates among Cystic Fibrosis Patients at a Referral Center for Lung Transplantation
- The chronic mental hospital population: a six-year follow-up study.