Haemodynamic effects of oral aminorex and amphetamine in unanaesthetized beagle dogs
AUTOR(ES)
Will, James A.
RESUMO
The haemodynamic effects of four daily oral doses of 1·5 mg/kg of aminorex (as fumarate) were measured in unanaesthetized beagle dogs. A similar study was performed in another group of related animals using d-amphetamine sulphate (1 mg/kg). Both agents produced similar sympathomimetic effects consisting of transient rises in systemic and pulmonary arterial blood pressures over an eight-hour period after administration of either drug. Heart rate remained unchanged in the dogs receiving aminorex whereas it decreased in those receiving amphetamine.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=472480Documentos Relacionados
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