Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.
AUTOR(ES)
Alfa, M J
RESUMO
Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, produces several factors that damage human cells. We used isogenic mutants of H. ducreyi 35000 to demonstrate that the hemolytic activity and the cytotoxic effect of H. ducreyi on human foreskin fibroblasts are due to the same toxin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174078Documentos Relacionados
- Characteristics of Haemophilus ducreyi in culture.
- A diffusible cytotoxin of Haemophilus ducreyi
- Haemophilus ducreyi, a cytotoxin-producing bacterium.
- Target Cell Range of Haemophilus ducreyi Hemolysin and Its Involvement in Invasion of Human Epithelial Cells
- Haemophilus ducreyi adheres to but does not invade cultured human foreskin cells.
