Hemolytic activity of the Pasteurella haemolytica leukotoxin.
AUTOR(ES)
Murphy, G L
RESUMO
A Pasteurella haemolytica mutant incapable of producing leukotoxin was created by allelic replacement. Concentrated culture supernatants from wild-type P. haemolytica, but not from the mutant, contained the 102-kDa leukotoxin protein and lysed bovine lymphoma cells and sheep erythrocytes. Wild-type P. haemolytica demonstrated the typical beta-hemolytic phenotype on sheep and rabbit blood agar, whereas the mutant did not.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=173439Documentos Relacionados
- Secretion and expression of the Pasteurella haemolytica Leukotoxin.
- Identification and characterization of the Pasteurella haemolytica leukotoxin.
- Activation of bovine neutrophils by partially purified Pasteurella haemolytica leukotoxin.
- Characterization of a neutralizing monoclonal antibody to Pasteurella haemolytica leukotoxin.
- Regulation of major histocompatibility complex class II expression by Pasteurella haemolytica leukotoxin.
