Host Cell Fate on Cryptosporidium parvum Egress from MDCK Cells

AUTOR(ES)

Elliott, David A.

FONTE

American Society for Microbiology

RESUMO

Cryptosporidium parvum is an intracellular protozoan parasite that causes a severe diarrheal illness of unclear etiology. Also unclear is the fate of the host cell upon parasite egress. We show in an MDCK cell model that the host cell is killed upon parasite egress; this death is necrotic, rather than apoptotic, in nature.

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