Host Response to a dam Mutant of Salmonella enterica Serovar Enteritidis with a Temperature-Sensitive Phenotype
AUTOR(ES)
Giacomodonato, Mónica N.
FONTE
American Society for Microbiology
RESUMO
The temperature-sensitive dam mutant strain of Salmonella enterica serovar Enteritidis SD1 is highly attenuated and induces innate and protective immunity in mice. SD1 activates NF-κB and induces gamma interferon secretion. Early interaction of the SD1 mutant with intestinal epithelial cells was associated with ruffling of enterocytes. Invading bacteria were found inside Peyer's patches after inoculation.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=517460Documentos Relacionados
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