Hypoglycemic Activity of Endotoxin II. Mechanism of the Phenomenon in BCG-infected Mice
AUTOR(ES)
Shands, J. W.
RESUMO
The mechanism of the hypoglycemic activity of endotoxin in hyperreactive BCG mice was investigated. The mechanism was found to be an inhibition of the synthesis of glucose from noncarbohydrate sources. The possibilities of an induced hypermetabolic state and an induced release of insulin in response to endotoxin as causes for the hypoglycemic response were essentially ruled out. In addition, no clear-cut evidence of an insulin-like action by endotoxin was found in the in vivo setting.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=284844Documentos Relacionados
- Suppressor T-cells in BCG-infected mice.
- Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice.
- Enhancement of resistance to infections by endotoxin-induced serum factor from Mycobacterium bovis BCG-infected mice.
- Ability of Post-endotoxin serum from BCG-infected mice to induce nonspecific resistance and stimulation of granulopoiesis.
- Suppression of babesiosis in BCG-infected mice and its correlation with tumor inhibition.