Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays

AUTOR(ES)

Decraene, Charles

FONTE

BioMed Central

RESUMO

A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the criteria for differential hybridization, 10 correspond to genes previously involved in C2-ceramide or TNF-α signaling pathways and 20 in neuronal disorders, oncogenesis or more broadly in the regulation of proliferation.

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