Immunodepression by Rowson-Parr virus in mice; lymphocyte markers and capping response of spleen and lymph node cells after infection.
AUTOR(ES)
Bendinelli, M
RESUMO
Infection with Rowson-Parr virus (RPV) induced a rapid reduction in the number of immunoglobulin-positive and theta antigen-positive cells detectable by immunofluorescence in the spleens of susceptible BALB/c mice. The changes produced by RPV infection in the lymph nodes were different, since the number of immunoglobulin-positive cells was increased and the proportion of theta-positive cells remained unchanged. However, the ability of immunoglobulin-bearing cells to redistribute their receptors into caps was reduced in both types of lymphoid tissue. A similar pattern of changes was produced by infection with Friend leukemia complex, from which RPV was originally obtained. These effects of RPV and Friend leukemia complex may contribute to the immunodepressed state of infected mice.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=420929Documentos Relacionados
- Immunodepression by Rowson-Parr Virus in Mice. II. Effect of Rowson-Parr Virus Infection on the Antibody Response to Sheep Red Cells In Vivo and In Vitro
- Immunodepression by Rowson-Parr Virus in Mice. I. Growth Curves of Rowson-Parr Virus and Immunological Relationships with Friend Virus
- Immunodepression by Rowson-Parr virus in mice: effect of Rowson-Parr virus and Friend leukemia complex infections on background antibody-forming cells to various erythrocytes.
- Immunodepression by Rowson-Parr virus in mice: effect of Rowson-Parr virus and Friend leukemia complex infections on contact sensitivity in susceptible and resistant mice.
- Effect of Friend Leukemia Virus and Rowson-Parr Virus on Immunological Maturation of Mice