Immunological abnormalities and HLA antigen frequencies in IgA deficient patients with epilepsy.
AUTOR(ES)
Fontana, A
RESUMO
Twenty-three epileptics with constitutional factors for seizures and low IgA serum concentrations were studied. Imbalance of the IgG subclasses was often observed, the IgG4 being undetectable in 13 (65%) patients. The percentage of circulating lymphocytes positive for surface immunoglobulins was normal except for slightly increased values for IgA in six (28.5%) patients. Of the epileptics, 48% showed subnormal proportions of lymphocytes forming spontaneous rosettes. There was a distinct trend for HLA-A2 antigen in the patients tested.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=493101Documentos Relacionados
- Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy.
- HLA antigen frequencies in flax byssinosis patients.
- Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies
- Carbamazepine-viloxazine interaction in patients with epilepsy.
- Impaired IgA class switching in APRIL-deficient mice