In Vitro Activities of 15 Antimicrobial Agents against Clinical Isolates of South African Enterococci

AUTOR(ES)

Struwig, M. C.

FONTE

American Society for Microbiology

RESUMO

The activities of a panel of currently available antibiotics and the investigational agents LY 333328, linezolid, CL 331,002, CL 329,998, moxifloxacin (BAY 12-8039), trovafloxacin, and quinupristin-dalfopristin against 274 clinical isolates of enterococci were determined. No vancomycin resistance or β-lactamase production was observed. Except for 12 isolates (all non-Enterococcus faecalis) showing reduced susceptibility to quinupristin-dalfopristin (MIC, ≥4 μg/ml), the new agents exhibited promising in vitro antienterococcal activity.

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