In Vitro Activity of BAY 12-8039, a New Fluoroquinolone, against Mycoplasmas
AUTOR(ES)
Bébéar, C. M.
FONTE
American Society for Microbiology
RESUMO
The in vitro activity of the fluoroquinolone BAY 12-8039 against 66 strains of different mycoplasma species and 30 strains of Ureaplasma urealyticum was compared with those of three other antimicrobial agents. BAY 12-8039 at 0.5 μg/ml inhibited 100% of all the mycoplasmal and ureaplasmal strains tested. The minimal bactericidal concentrations of BAY 12-8039 increased only two- to eightfold compared to the MICs. Furthermore, they were comparable to those of sparfloxacin and lower than those of doxycycline and clarithromycin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105523Documentos Relacionados
- In vitro activity of BAY 12-8039, a new fluoroquinolone.
- In vitro activity of Bay 12-8039, a new 8-methoxyquinolone.
- In Vitro Activity of a New 8-Methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae
- Comparison of the in vitro activities of Bay 12-8039, a new quinolone, and other antimicrobials against clinically important anaerobes.
- In Vitro Susceptibilities of Bordetella pertussis and Bordetella parapertussis to BAY 12-8039, Trovafloxacin, and Ciprofloxacin