In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer.
AUTOR(ES)
Rolston, K V
RESUMO
The in vitro activity of paldimycin, a novel antimicrobial agent, was compared with that of vancomycin against 306 gram-positive isolates (representing 12 bacterial species) obtained from patients with cancer. Paldimycin had lower MICs for 90% of isolates than vancomycin did against most isolates tested. Its activity, however, was medium and pH dependent, being greatest in Nutrient broth at a pH of 6.8.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=174800Documentos Relacionados
- In vitro activities of daptomycin (LY146032) and paldimycin (U-70,138F) against anaerobic gram-positive bacteria.
- In vitro activity of LY264826, a new glycopeptide antibiotic, against gram-positive bacteria isolated from patients with cancer.
- In vitro susceptibility of gram-positive cocci to paldimycin.
- In vitro activity of U-57930E, a new clindamycin analog, against aerobic gram-positive bacteria.
- In vitro activity of biapenem against clinical isolates of gram-positive and gram-negative bacteria.
