In vitro activity of ramoplanin against vancomycin-resistant gram-positive organisms.
AUTOR(ES)
Collins, L A
RESUMO
In vitro activity of ramoplanin, a cyclic lipoglycopeptide, against 92 vancomycin-resistant gram-positive organisms was evaluated. Ramoplanin demonstrated potent activity against many highly vancomycin-resistant organisms including enterococci (MICs for 90% of strains tested of 0.5 micrograms/ml) and against Lactobacillus spp., Leuconostoc spp., and Pediococcus spp., all of which were inhibited at concentrations of < or = 0.25 micrograms/ml. This drug or a derivative compound merits further investigation as a potential therapeutic agent for infections due to vancomycin-resistant enterococci.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=187967Documentos Relacionados
- In vitro activity of RP59500, an injectable streptogramin antibiotic, against vancomycin-resistant gram-positive organisms.
- Activity of glycopeptides against vancomycin-resistant gram-positive bacteria.
- Recovery of vancomycin-resistant gram-positive cocci from children.
- In vitro activities of daptomycin and other antimicrobial agents against vancomycin-resistant gram-positive bacteria.
- In Vitro Activities of Linezolid against Important Gram-Positive Bacterial Pathogens Including Vancomycin-Resistant Enterococci