In vitro bioactivity of PMMA-based composite in simulated plasma with albumin
AUTOR(ES)
Lopes, Poliana P., Leite Ferreira, Bárbara J. M., Almeida, Nuno A. F., Silva, Tatiane E., Fredel, Márcio C., Fernandes, Maria Helena F. V., Correia, Rui N.
FONTE
Matéria (Rio de Janeiro)
DATA DE PUBLICAÇÃO
2007
RESUMO
A new composite of poly(methyl methacrylate) - co -(ethyl-hexyl-acrylate) filled with glass of composition (wt.%) 61,33% 3CaO.P2O5 - 23,03% SiO2 - 15,64% MgO was developed. The formation of CaP (calcium phosphate) layers on implants is crucial for their integration in bone. Simulated biological fluids to study in vitro formation of those layers do not usually contain important organic substances, such as proteins. In the present work in vitro bioactivity was studied in a simulated body fluid in presence (SBFA) and in absence of albumin (SBF). The effect of protein on calcium phosphate formation was followed by ion concentration analyses (ICP), X-ray diffraction (XRD) and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy (SEM-EDS). The results showed the precipitation of a CaP layer on the composite in SBFA. Further crystallization of this layer, initially amorphous, seems to be hindered by the presence of albumin.
Documentos Relacionados
- Repair Strength in Simulated Restorations of Methacrylate- or Silorane-Based Composite Resins
- PMMA/Ca2+ bone cements. Hydrolytic properties and bioactivity
- Tooth Discoloration Using Calcium Silicate-Based Cements For Simulated Revascularization in Vitro
- In vitro bioactivity of polymer matrices reinforced with a bioactive glass phase
- Development and characterization of stuff composite to based on PMMA reinforced with fiberglass for use odontologic