In vitro inhibition of adhesion of Escherichia coli strains by Xylitol

AUTOR(ES)

Silva, Annelisa Farah da, Suzuki, Érika Yoko, Ferreira, Aline Siqueira, Oliveira, Murilo Gomes, Silva, Sílvio Silvério da, Raposo, Nádia Rezende Barbosa

FONTE

Brazilian Archives of Biology and Technology

DATA DE PUBLICAÇÃO

2011-04

RESUMO

The present study aimed to evaluate xylitol's antimicrobial and anti-adherence activities on Escherichia coli (ATCC 8739) and on another clinical strain enteropathogenic E. coli (EPEC). In vitro minimum inhibitory concentration (MIC) test and adhesion assays were performed using 0.5, 2.5 and 5.0% xylitol. It was found that xylitol did not have antimicrobial properties on these strains. The scanning electron microscopy (SEM) demonstrated that the slides treated with xylitol had a significant reduction in the number of bacilli and the inhibition of microbial adhesion was probably the xylitol's mechanism of action. Xylitol could be a possible alternative on the control of E. coli infections.

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