Increased loss of duplicated genes in streptomycin-resistant (strA) mutants of Escherichia coli k-12.

AUTOR(ES)

Simonian, M H

RESUMO

The recombination-dependent loss of a duplicated portion of the Escherichia coli chromosome is five- to tenfold greater in strains containing streptomycin resistance (strA) mutations than in the strA+ parental strain. Streptomycin (500 mug/ml) partially reverses the increase. These results suggest an interaction between strA mutations and recombination.

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