Increased prolactin response to thyrotropin releasing hormone during migraine attacks.
AUTOR(ES)
Papakostas, Y
RESUMO
Prolactin (PRL) has been associated with the pathogenesis of migraine, and various approaches have been used to investigate its role. In the present study, the PRL response to thyrotropin-releasing hormone (TRH) was evaluated in eight women migraineurs during an attack-free state and during a migraine attack. PRL baseline values were not different in the two states, and the same was true for the TSH responses to TRH. The PRL responses to TRH were, however, significantly higher during the attack, a finding that indicates a latent disturbance of the PRL-regulating systems in migraine, with a higher responsiveness during migraine attacks.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1032136Documentos Relacionados
- Thyroid Hormone Inhibition of the Prolactin Response to Thyrotropin-Releasing Hormone
- Temporal lobe phenomena during the aura phase of migraine attacks.
- Inhibition of thyrotropin response to thyrotropin-releasing hormone by small quantities of thyroid hormones
- Thyrotropin-releasing hormone exerts rapid nuclear effects to increase production of the primary prolactin mRNA transcript.
- Variable Thyrotropin Response to Thyrotropin-releasing Hormone after Small Decreases in Plasma Free Thyroid Hormone Concentrations in Patients with Nonthyroidal Diseases