Induction of early-phase endotoxin tolerance in athymic (nude) mice, B-cell-deficient (xid) mice, and splenectomized mice.
AUTOR(ES)
Madonna, G S
RESUMO
Early-phase endotoxin tolerance was inducible in mice which were T cell deficient (nude), B cell deficient (xid), or asplenic, which suggests that these lymphoid cell subsets and the spleen do not contribute significantly to the induction of acquired lipopolysaccharide hyporesponsiveness. C3H/HeJ mice did not exhibit the hematopoietic changes observed in mice made endotoxin tolerant, which suggests that multiple mechanisms may underlie lipopolysaccharide hyporesponsiveness.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260853Documentos Relacionados
- Chronic giardiasis in B-cell-deficient mice expressing the xid gene.
- Trypanosoma musculi infection in B-cell-deficient mice.
- Trypanosoma rhodesiense infection in B-cell-deficient mice.
- Experimental cryptococcosis in normal and B-cell-deficient mice.
- Giardia lamblia infections in B-cell-deficient transgenic mice.
