INDUCTION OF MELANIN SYNTHESIS IN ALBINO MOUSE SKIN BY DNA FROM PIGMENTED MICE*
AUTOR(ES)
Ottolenghi-Nightingale, Elena
RESUMO
Skin cells from albino mouse embryos have been shown to synthesize melanin after exposure to a nucleoprotein fraction of cells from pigmented mice. Although transformed clones were not found in any of 37 control experiments, at least 15 transformations took place in 10 of a series of 49 experiments using undegraded DNA. The active component in the transforming material appears to be DNA because DNase-treated preparations did not induce melanin synthesis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=286145Documentos Relacionados
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