Induction of proteins in response to low temperature in Escherichia coli.

AUTOR(ES)

Jones, P G

RESUMO

When the growth temperature of an exponential culture of Escherichia coli is abruptly decreased from 37 to 10 degrees C, growth stops for several hours before a new rate of growth is established. During this growth lag the number of proteins synthesized is dramatically reduced, and at one point only about two dozen proteins are made; 13 of these are made at differential rates that are 3 to 300 times increased over the rates at 37 degrees C. The protein with the highest rate of synthesis during the lag is not detectably made at 37 degrees C. The identities of several of these cold shock proteins correlate with previous observations that indicate a block in translation initiation at low temperatures.

Documentos Relacionados

• Low-temperature conditional cell division mutants of Escherichia coli.
• Identification and characterization of novel low-temperature-inducible promoters of Escherichia coli.
• Transient response to chemotactic stimuli in Escherichia coli.
• Stabilization of apoglobin by low temperature increases yield of soluble recombinant hemoglobin in Escherichia coli.
• Induction of autolysis in nongrowing Escherichia coli.