Infection by HTLV-2 in pregnant women of Mato Grosso do Sul. / Infecção pelo HTLV 1-2 em Gestantes de Mato Grosso do Sul

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

Objective: The aimed at studying the epidemiologic, virology and genotype conducts of HTLV in diagnosed pregnant women of Mato Grosso do Sul during the prenatal, and their children, born between November 2002 and December 2005. Methodology : There have been inserted HTLV 1/2 infection-diagnosed women detected by ELISA, Western Blot and PCR techniques assisted by The Expectant Mother Protection Program (Programa de Proteção à Gestante) of the State of Mato Grosso do Sul, between November 2002 and December 2005. On the purpose of defining and excluding the infection in a child, PCR tests were performed at birth, at the age of 2 and 4 months; ELISA and Western Blot at 12 months, and after 18 months old when not breast-fed. Results: 116.689 pregnant women were examined, being 153 HTLV infection-diagnosed, with prevalence of 0.13%; 73.2% were black, pale or indigenous indian skinned, about 90% reported on household chores and 75.8% reported on holding 7 (seven) years or less education. Concerning the pregnancies followed up, 6.7% (11/164) evolved to abortion and co-morbidities were noticed in 17.0% (26/153) being 3.3% (5/153) with HIV (p<0.000002). Concerning the children, 123 live-birth were inserted, where 5 of them died at their first age and 7 are waiting for positive diagnosis. Infection has been confirmed in 8 children, which reached 7.2% (8/111) vertical transmission rate. Conclusion: There hasnt been noticed a meaningful difference related to the maternal and children variables, which can be due to the restricted amount of samples studied. New studies are necessary to know the risk factors to the HTLV vertical transmission, cohort studies with clinical protocol that observe the possible role of the antigenemy and mother-antibodies title during pregnancy, type of delivery and period of breast-feeding. It is better to implement anti-HTLV testing in all women during the prenatal, research and treatment of co-morbidities, avoid maternal secretions contact pointing to elective delivery, immediate child bath, breast-feeding suspension, as well as the formula (baby) milk supply.

ASSUNTO(S)

infecções por htlv-1/epidemiologia htlv-ii infections/epidemiology htlv-ii infections/epidemiology htlv-i infections/diagnosis infecções por htlv-2/disgnóstico htlv-ii infections/diagnosis infecções por htlv-1/diagnóstico gestantes pregnant women doencas infecciosas e parasitarias infecções por htlv-2/epidemiologia

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