Infective Substructures of Sendai Virus from Infected Ehrlich Ascites Tumor Cells
AUTOR(ES)
Bukrinskaya, A. G.
RESUMO
Increase of infectivity for embryonated eggs was observed in Ehrlich ascites tumor cells after intraperitoneal inoculation of Sendai virus into tumor-bearing mice. Virus-induced actinomycin-resistant ribonucleic acid consisting of 14S, 18S, 22S, 35S, and 48S was synthesized, and S antigen was produced in infected cells. The infectivity was suggested to be due to viral ribonucleoprotein for the following reasons: (i) the infectivity was unaffected by V antiserum but was abolished by whole hyperimmune serum, (ii) the infectivity was resistant to ribonuclease, (iii) virus particles were found neither in cells nor on red blood cell stroma treated with cellular extracts, (iv) structures similar to Sendai virus ribonucleoprotein with a maximal length of 10,500 A were observed in cellular extracts.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=375684Documentos Relacionados
- Infective substructures of measles virus from acutely and persistently infected cells.
- STUDIES ON RIBONUCLEIC ACID ISOLATED FROM EHRLICH ASCITES TUMOR CELLS
- Purification and properties of a nuclear exoribonuclease from Ehrlich ascites tumor cells.
- Preservation of Ehrlich ascites tumor cells with dimethyl sulfoxide.
- 31P nuclear magnetic resonance studies of Ehrlich ascites tumor cells.