Ingi, a 5.2-kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs.
AUTOR(ES)
Kimmel, B E
RESUMO
A dispersed repetitive element named ingi, which is present in the genome of the protozoan parasite Trypanosoma brucei, is described. One complete 5.2-kilobase element and the ends of two others were sequenced. There were no direct or inverted terminal repeats. Rather, the ends consisted of two halves of a previously described 512-base-pair transposable element (G. Hasan, M.J. Turner, and J.S. Cordingley, Cell 37:333-341, 1984). Oligo(dA) tails and possible insertion site duplications suggested that ingi is a retroposon. The sequenced element appears to be a pseudogene copy of an original retroposon with one or more open reading frames occupying most of its length. Significant homologies of the encoded amino acid sequences with reverse transcriptases and mammalian long interpersed nuclear element sequences suggest a remote evolutionary origin for this kind of retroposon.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=365235Documentos Relacionados
- SLACS retrotransposon from Trypanosoma brucei gambiense is similar to mammalian LINEs.
- Authentic reverse transcriptase is coded by jockey, a mobile Drosophila element related to mammalian LINEs.
- Ribosomal RNA genes of Trypanosoma brucei. Cloning of a rRNA gene containing a mobile element.
- Mobile dispersed genetic element MDG1 of Drosophila melanogaster: nucleotide sequence of long terminal repeats.
- The spliced leader sequence of Trypanosoma brucei has a potential role as a cap donor structure.
