Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene.

AUTOR(ES)
RESUMO

Ajoene, a garlic-derived compound that prevents platelet activation, inhibited the growth of Paracoccidioides brasiliensis, a fungal pathogen for humans, by affecting the integrity of the fungal cytoplasmic membrane. This action may be the basis for the study of ajoene as a possible specific antifungal drug.

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