Inhibitory effect of cephalosporins on gamma-aminobutyric acid receptor binding in rat synaptic membranes.
AUTOR(ES)
Hori, S
RESUMO
Cephalosporins inhibited gamma-aminobutyric acid receptor binding in a concentration-dependent manner in vitro. Scatchard analysis revealed that cefazolin decreased the binding capacity but did not change the affinity of the receptor. It is suggested that this inhibition of gamma-aminobutyric acid receptor binding may be involved in the induction of convulsions by cephalosporins.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=180115Documentos Relacionados
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