Interaction of DNA with a porphyrin ligand: evidence for intercalation.
AUTOR(ES)
Fiel, R J
RESUMO
The porphyrin photosensitizer, meso-Tetra (4-N-methylpyridyl) porphine tetraperchlorate binds to calf thymus DNA by intercalation and by external electrostatic association. This was concluded from the results of measruements involving Scatchard analysis, viscometry, thermal denaturation, and circular dichroism.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=327919Documentos Relacionados
- A molecular model for proflavine-DNA intercalation.
- Fast photoinduced electron transfer through DNA intercalation.
- Binding of ethidium and bis(methidium)spermine to Z DNA by intercalation.
- Ellipticine increases the superhelical density of intracellular SV40 DNA by intercalation.
- Molecular mechanical studies of proflavine and acridine orange intercalation.
