Interactions of Vestigial and Scabrous with the Notch Locus of Drosophila Melanogaster

AUTOR(ES)

Rabinow, L.

RESUMO

Interactions are described between the Notch locus of Drosophila melanogaster, and two other loci, scabrous and vestigial, which respectively affect the eyes and wings. The Notch locus is responsible for mediating decisions of cell fate throughout development in many different tissues. Mutations and duplications of vestigial and scabrous alter the severity of phenotypes associated with Notch mutations and duplications in a manner that is essentially tissue- and allele-specific. These interactions indicate that the products of vestigial and scabrous act in conjunction with Notch to stimulate the differentiation of specific cell types.

Documentos Relacionados

• Targeted Transposition at the Vestigial Locus of Drosophila Melanogaster
• Negative Complementation at the Notch Locus of DROSOPHILA MELANOGASTER
• Temperature-Sensitive Mutations of the Notch Locus in DROSOPHILA MELANOGASTER
• A Genetic Analysis of Deltex and Its Interaction with the Notch Locus in Drosophila Melanogaster
• Deltex, a Locus Interacting with the Neurogenic Genes, Notch, Delta and Mastermind in Drosophila Melanogaster