Interview: Bioreactors and Surfaced-Modified 3D-Scaffolds for Stem Cell Research

AUTOR(ES)

Weibezahn, Karl-Friedrich

FONTE

MyJove Corporation

RESUMO

A Nature Editorial in 2003 asked the question "Good-bye, flat biology?" What does this question imply? In the past, many in vitro culture systems, mainly monolayer cultures, often suffered from the disadvantage that differentiated primary cells had a relatively short life-span and de-differentiated during culture. As a consequence, most of their organ-specific functions were lost rapidly. Thus, in order to reproduce better conditions for these cells in vitro, modifications and adaptations have been made to conventional monolayer cultures.

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