Intracellular Crystal Formation as a Mechanism of Cytotoxicity in Murine Pulmonary Cryptococcus neoformans Infection
AUTOR(ES)
Feldmesser, Marta
FONTE
American Society for Microbiology
RESUMO
Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=98213Documentos Relacionados
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