Intracellular Inactivation of Bacteriophage T4 Early Deoxyribonucleic Acid

AUTOR(ES)

Mathews, Christopher K.

RESUMO

As previously shown, a small amount of polynucleotide material is added to parental T4 deoxyribonucleic acid (DNA) molecules within the first 5 min of infection. I have asked whether this process is essential for phage replication. Two approaches—one involving decay of 32P incorporated into this “early DNA” and the other involving photoinactivation of bromodeoxyuridine-containing early DNA—indicate that it is.

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