Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers.

AUTOR(ES)

Higgins, P G

RESUMO

In a double-blind, placebo-controlled study, self-administered intranasal human interferon alpha A produced by recombinant DNA technology was given both before and after virus challenge with a respiratory coronavirus. The incidence of colds, the severity of symptoms and signs, and virus replication were all reduced in subjects receiving interferon as compared with those given placebo.

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