Invasive Infection with Fusarium chlamydosporum in a Patient with Aplastic Anemia
AUTOR(ES)
Segal, Brahm H.
FONTE
American Society for Microbiology
RESUMO
We report the first case of invasive disease caused by Fusarium chlamydosporum. The patient had aplastic anemia with prolonged neutropenia and was treated with immunosuppressive therapy. While she was receiving empirical amphotericin B, a dark crusted lesion developed on her nasal turbinate. Histologic analysis revealed invasive hyaline hyphae and some darkly pigmented structures that resembled conidia of dematiaceous molds. Only after the mold was grown in culture were characteristic colonial morphology, phialides, conidia, and chlamydospores evident, thus permitting the identification of F. chlamydosporum. This case illustrates the ever-increasing spectrum of pathogenic Fusarium spp. in immunocompromised patients and emphasizes the potential pitfalls in histologic diagnosis, which may have important treatment implications.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=104919Documentos Relacionados
- Trichoderma longibrachiatum infection in a pediatric patient with aplastic anemia.
- Soft Tissue Infection with Absidia corymbifera in a Patient with Idiopathic Aplastic Anemia
- Catheter-associated fungemia caused by Fusarium chlamydosporum in a patient with lymphocytic lymphoma.
- Vision loss following snakebite in a patient with controlled aplastic anemia
- Parvovirus infection associated with aplastic crisis in a patient with HEMPAS.