Is House-Dust Nicotine a Good Surrogate for Household Smoking?

AUTOR(ES)

Whitehead, Todd

FONTE

Oxford University Press

RESUMO

The literature is inconsistent regarding associations between parental smoking and childhood leukemia, possibly because previous studies used self-reported smoking habits as surrogates for children's true exposures to cigarette smoke. Here, the authors investigated the use of nicotine concentrations in house dust as measures of children's exposure to cigarette smoke in 469 households from the Northern California Childhood Leukemia Study (1999–2007). House dust was collected by using high-volume surface samplers and household vacuum cleaners and was analyzed for nicotine via gas chromatography–mass spectrometry. Using multivariable linear regression, the authors evaluated the effects of self-reported parental smoking, parental demographics, house characteristics, and other covariates on house-dust nicotine concentrations. They observed that nicotine concentrations in house dust were associated with self-reported smoking for periods of months and years before dust collection. Furthermore, the authors found that the relation between nicotine dust levels and self-reported smoking varied by parental age and socioeconomic status. These findings suggest that house-dust nicotine concentrations reflect long-term exposures to cigarette smoke in the home and that they may be less biased surrogates for children's exposures to cigarette smoke than self-reported smoking habits.

Documentos Relacionados

• Bronchial Sensitivity Testing in Asthma: An Assessment of the Effect of Hyposensitization in House-Dust and Pollen-sensitive Asthmatic Subjects
• Carry on smoking?
• Does ethnic ancestry play a role in smoking?
• Is thickening of the basal lamina in the saphenous vein a hallmark of smoking?
• Nicotine receptor partial agonists for smoking cessation