Isolation and Characterization of a sigB Deletion Mutant of Staphylococcus aureus
AUTOR(ES)
Nicholas, R. O.
FONTE
American Society for Microbiology
RESUMO
The sigB gene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mutant showed no reduction in virulence.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=116562Documentos Relacionados
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