Isolation and Characterization of Antibiotic LL-AC541

AUTOR(ES)

Zbinovsky, V.

RESUMO

A new basic, water-soluble antibiotic designated LL-AC541, produced by a strain of Streptomyces hygroscopicus (NRRL 3111), was isolated as a hydrochloride salt; [α]D25, — 58°, melting point, 200 to 215 C (decomposition). It is structurally related to streptothricin but does not contain β-lysine. Isolation procedures, physicochemical properties, antimicrobial spectrum, and in vivo testing results are presented. Another very closely related antibiotic obtained from the same fermentation is briefly described.

Documentos Relacionados

• Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities
• Isolation and Characterization of Integron-Containing Bacteria without Antibiotic Selection
• Screening, Fermentation, Isolation, and Characterization of Trypanomycin, a New Antibiotic
• Butirosin, a New Aminoglycosidic Antibiotic Complex: Isolation and Characterization
• LL-A491, A Monazomycin-like Antibiotic