Isolation of Chinese hamster ovary cells that overproduce asparaginyl-tRNA synthetase.

AUTOR(ES)
RESUMO

Temperature-resistant revertants, derived from the temperature-sensitive CHO asparaginyl-tRNA synthetase mutant, Asn-5, were isolated and characterized. Several lines of evidence indicate that the temperature-resistant phenotype of the revertants is due to their overproducing the same altered enzyme present in the Asn-5 parent.

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