Keratocystic odontogenic tumor related to nevoid basal cell carcinoma syndrome: clinicopathological study

AUTOR(ES)

Bomfin, Luana Eschholz, Vivas, Ana Paula M., Rocha, Andre Caroli, Achatz, Maria Isabel W., Pinto, Clovis Antonio L., Alves, Fabio Abreu

FONTE

Braz. J. Oral Sci.

DATA DE PUBLICAÇÃO

2013-03

RESUMO

AIM: To assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with nevoid basal cell carcinoma syndrome (NBCCS) in a single Brazilian institution. METHODS: After histopathological analyses of KCOT related to NBCCS, the medical charts of 14 patients were assessed. These patients presented a total of 31 primary and 8 recurrent KCOT. RESULTS: Out of 14 patients, 8 presented a single KCOT, 4 showed synchronous tumors, 1 had 3 metachronous lesions and another patient had 2 synchronous lesions at initial evaluation and then developed other 3 metachronous lesions. Besides the 31 primary KCOTs, 18 lesions were located in mandible and 13 in maxilla. Most tumors presented unilocular pattern and association with a tooth. CONCLUSIONS: KCOT is a frequent manifestation of NBCCS and can be its first sign, mainly in young patients. In contrast to a previously published series, most patients presented a single lesion.

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