Killing of Staphylococcus aureus by C-8-Methoxy Fluoroquinolones
AUTOR(ES)
Zhao, Xilin
FONTE
American Society for Microbiology
RESUMO
C-8-methoxy fluoroquinolones were more lethal than C-8-bromine, C-8-ethoxy, and C-8-H derivatives for Staphylococcus aureus, especially when topoisomerase IV was resistant. The methoxy group also increased lethality against wild-type cells when protein synthesis was inhibited. These properties encourage refinement of C-8-methoxy fluoroquinolones to kill staphylococci.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=105579Documentos Relacionados
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