Kinetics of Insulin Release from the Perfused Rat Pancreas Caused by Glucose, Glucosamine, and Galactose
AUTOR(ES)
Landgraf, Rüdiger
RESUMO
Under appropriate conditions, not only glucose but also glucosamine and galactose can serve as potent stimulants for insulin release from the isolated, perfused rat pancreas. Since galactose and, probably, glucosamine are not metabolized in the islets, and since these three compounds have in all likelihood common sites of action, it is postulated that a glucoreceptor of broad specificity is involved in the mechanism of insulin release, and that metabolism of glucose is not an essential part of the releasing action of this sugar.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=388982Documentos Relacionados
- Characterization of the Effects of Arginine and Glucose on Glucagon and Insulin Release from the Perfused Rat Pancreas
- Effect of glucose/sulfonylurea interaction on release of insulin, glucagon, and somatostatin from isolated perfused rat pancreas.
- Glucose Modulation of Amino Acid-Induced Glucagon and Insulin Release in the Isolated Perfused Rat Pancreas
- Effect of age and environmental factors on insulin release from the perfused pancreas of the rat.
- Glucagon Secretion from the Perfused Rat Pancreas STUDIES WITH GLUCOSE AND CATECHOLAMINES
