Lack of C-erbB-2 protein expression in pulmonary carcinoid tumours.
AUTOR(ES)
Wilkinson, N
RESUMO
To determine if amplification of the C-erb-B2 proto-oncogene could be correlated with prognosis in carcinoid tumours, 49 pulmonary carcinoid tumours (26 typical, 23 atypical) were examined using a polyclonal antibody to the C-terminal peptide of the C-erb-B2 protein sequence. No C-erb-B2 gene product could be shown: the demonstration of C-erb-B2 does not seem to help, therefore, in determining diagnosis or prognosis in pulmonary carcinoid tumours.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=496917Documentos Relacionados
- Lack of c-erbB-2 oncoprotein expression in male breast carcinoma.
- Prognostic value of c-erbB-2 expression in uterine cervical carcinoma.
- c-erbB-2 oncogene product expression and prognosis in gastric carcinoma.
- c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors
- C-erbB-2 immunostaining: problems with interpretation.