Lack of complex I is associated with oncocytic thyroid tumours
AUTOR(ES)
Zimmermann, F A
FONTE
Nature Publishing Group
RESUMO
Oncocytic tumours are characterised by hyperproliferation of mitochondria. We immunohistochemically analysed all enzymes of the oxidative phosphorylation system in 19 oncocytic thyroid tumours. A specific lack of complex I was detected, which was expressed at <5% of the level determined in surrounding non-cancerous tissue.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2694433Documentos Relacionados
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